LNCRNA EBLN3P ATTRIBUTES METHOTREXATE RESISTANCE IN OSTEOSARCOMA CELLS THROUGH MIR-200A-3P/O-GLCNAC TRANSFERASE PATHWAY

LncRNA EBLN3P attributes methotrexate resistance in osteosarcoma cells through miR-200a-3p/O-GlcNAc transferase pathway

Abstract Background Osteosarcoma is highly malignant.The migration, invasion, and chemoresistance contribute to poor prognosis of osteosarcoma.Research reported that endogenous bornavirus-like Tridonic PC Combo nucleoprotein 3 pseudogene (EBLN3P) promotes the progression of osteosarcoma.Methods In this study, the expression of EBLN3P in osteosarcom

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TEACHING ORGANIZATIONAL STRUCTURE THROUGH THE CASE METHOD

Teaching at Soap university level has evolved in recent years towards teaching methodologies in which the student has an increasingly active role in their learning, being the protagonist together with the teaching staff.The use of techniques in which students put into practice and reflect on the theoretical contents has benefits both for the acquis

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Smooth ROC curve estimation via Bernstein polynomials.

The receiver operating characteristic (ROC) curve is commonly used to evaluate the accuracy of a diagnostic test for classifying observations into two groups.We propose two novel tuning parameters for estimating the ROC curve via Bernstein polynomial smoothing of the empirical ROC curve.The new estimator is very easy to implement with the naturally

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